What is the street address of Dr. Gregory House’s apartment in House M.D.?

Dr. Gregory House’s apartment address in House M.D. is 221B Baker Street.

The address is a deliberate reference to Sherlock Holmes, the fictional detective whose methods and personality inspired House. In Arthur Conan Doyle’s stories, Holmes lives at 221B Baker Street in London with Dr. John Watson. House’s own name and his friendship with James Wilson continue the same pattern of literary echoes.

In the television series, House’s apartment is presented in Princeton, New Jersey, rather than London. The address therefore functions as an allusion, not as a claim that House lives in the original Sherlock Holmes setting.

The number is often recognized even by people who have never read the stories, because 221B Baker Street has become one of fiction’s most famous addresses. House M.D. uses the reference to signal that its medical cases are structured like detective mysteries, with symptoms serving as clues.