What is the name of House’s drug addiction in House M.D.?

House’s drug addiction in House M.D. centers on Vicodin.

Vicodin is a prescription pain medication containing hydrocodone and paracetamol, also called acetaminophen. In the series, House uses it to manage chronic pain caused by an infarction in the quadriceps muscle of his right thigh. His reliance on the drug becomes one of the show’s longest-running personal and medical conflicts.

The addiction affects House’s judgment, relationships, employment, and medical license. Several storylines show attempts to stop or control his use, along with relapses and consequences. The medication is therefore not merely a character detail; it is a continuing source of tension in the series.

A common mix-up is to identify House’s drug simply as a generic opioid or to name another painkiller. Vicodin is the specific branded medication repeatedly associated with him. Its formulation and availability have varied by market and over time, but the show consistently uses the name Vicodin for House’s habitual pain medicine.