What is the name of House's apartment street address in House M.D.?

House’s apartment address in House M.D. is 221B Baker Street.

The address is a deliberate reference to Sherlock Holmes, whose fictional London home is famously 221B Baker Street. Gregory House is modeled partly on Holmes: both are highly analytical, socially abrasive investigators who solve difficult problems through observation and deduction. House adapts that detective structure to medicine, turning symptoms and test results into clues.

In the series, House’s apartment is in Princeton, New Jersey, so the Baker Street address is an allusion rather than a literal London location. The reference is one of several Holmes connections, alongside House’s surname, the character of James Wilson, and the use of music and behavior to suggest the detective’s influence.

Viewers sometimes confuse the address with Holmes’s residence as a real-world location. The number is part of the fictional tradition, although 221B Baker Street in London is now associated with the Sherlock Holmes Museum.