What is the name of Gregory House’s colleague and best friend in House M.D.?

James Wilson is Gregory House’s colleague and best friend in House M.D.

Wilson is an oncologist at Princeton-Plainsboro Teaching Hospital and is played by Robert Sean Leonard. His medical specialty gives him a different perspective from House’s diagnostic work, while his empathy often balances House’s abrasive behavior.

The friendship is central to the series. Wilson repeatedly helps House, challenges his decisions, and remains connected to him despite House’s dishonesty and destructive habits. Their relationship also supplies much of the show’s emotional storyline.

Viewers sometimes identify Wilson only by his surname because that is how House usually addresses him. His full character name is James Evan Wilson, but the canonical short answer to this question is James Wilson. Wilson’s final major story involves terminal thymoma, a cancer diagnosis revealed during the last season.