What is the name of Gregory House’s close friend in House M.D.?

James Wilson is Gregory House’s close friend in House M.D.

Wilson is an oncologist at Princeton-Plainsboro Teaching Hospital and serves as one of the few people willing to challenge House personally as well as professionally. Their friendship is a central relationship in the series, often balancing House’s cynicism with Wilson’s empathy and concern.

Robert Sean Leonard played Wilson throughout the series. Wilson’s medical specialty is oncology, meaning the diagnosis and treatment of cancer. His department gives him a different perspective from House’s diagnostic work, and he frequently helps interpret the human consequences of House’s decisions.

The character is often called simply “Wilson,” which can make the full name less familiar to casual viewers. He is not James Cameron, despite that character also appearing in House’s original diagnostic team. James Wilson is the canonical full name of House’s best-known friend.