The first name of House M.D. character Dr. Wilson is James.
James Wilson is Gregory House’s closest friend and a major supporting character in the series. He serves as the head of oncology at Princeton-Plainsboro Teaching Hospital, treating patients with cancer while also advising House during personal and professional crises.
Robert Sean Leonard played Wilson throughout the series. Wilson is generally more compassionate and socially conventional than House, but he is not simply House’s opposite: he can be evasive, impulsive, and morally complicated. Their friendship survives arguments, career changes, and House’s repeated disregard for ordinary boundaries.
The character’s full name is Dr. James Evan Wilson. Viewers sometimes identify him only by his surname because House almost always calls him “Wilson,” but James is the canonical first name used in character references and the series’ background material.