What is the fictional teaching hospital where most House M.D. cases take place?

Most House M.D. cases take place at Princeton-Plainsboro Teaching Hospital.

Princeton-Plainsboro is a fictional teaching hospital in New Jersey. It serves as the workplace for Gregory House, his diagnostic fellows, hospital administrator Lisa Cuddy, oncologist James Wilson, and many recurring physicians. The hospital’s teaching status helps explain why House works with changing teams of younger doctors.

The name combines “Princeton,” referencing the New Jersey setting, with “Plainsboro,” a nearby real municipality. It is not the same institution as Princeton University’s medical facilities, and the hospital itself was created for the series.

The hospital provides the show’s main setting for consultations, tests, surgeries, and administrative conflicts. Some episodes also move outside its walls, but Princeton-Plainsboro remains the central location throughout the series.