What is House M.D.'s first episode called?

House M.D.'s first episode is called “Pilot.” It serves as the series premiere and introduces Gregory House, his diagnostic colleagues, and the hospital setting that anchors the drama.

In the episode, House investigates the illness of Rebecca Adler, a kindergarten teacher who develops severe symptoms. The case demonstrates the show's central formula: House's team proposes diagnoses, tests produce unexpected results, and House uses deduction to identify the underlying disease.

The episode was written by series creator David Shore and directed by Bryan Singer. Its broadcast on Fox on November 16, 2004, began the show's eight-season run. The pilot also establishes House's reluctance to perform routine clinic work and his dependence on Vicodin for chronic pain.

“Pilot” is a conventional title for a first episode, so viewers sometimes confuse it with memorable early installments such as “Three Stories” or “Detox.” Those are separate episodes. “Three Stories” later became especially notable for its unusual structure and award recognition.