What fictional street address does House live at in House M.D.?

House lives at the fictional address 221B Baker Street in House M.D.

The address is a deliberate reference to 221B Baker Street, the London home of Sherlock Holmes in Arthur Conan Doyle’s stories. House’s investigative method, reliance on deduction, difficult personality, and surname also echo Holmes, making the address one of the show’s clearest literary clues.

In the series, House’s apartment is located in New Jersey despite the famous address being associated with London. The setting therefore functions primarily as an allusion rather than a realistic claim about the character’s geography.

Viewers may remember House’s address as a generic apartment number or confuse it with the address of another fictional detective. The canonical Holmes reference is “221B Baker Street,” and the show uses it to reinforce the connection between medical diagnosis and detective work.