What fictional New Jersey hospital is the main setting of House M.D.?

Princeton-Plainsboro Teaching Hospital is the fictional New Jersey hospital where most of House M.D. takes place. Dr. Gregory House leads the hospital's Department of Diagnostic Medicine there.

The institution is presented as a teaching hospital, allowing the series to combine advanced specialist care with House's team-based diagnostic investigations. The hospital's administrators, surgeons, oncologists, and other departments frequently become involved in the cases.

Although the hospital is fictional, its name reflects the real New Jersey communities of Princeton and Plainsboro. The series was filmed largely in California, with the exterior of a building at the University of Southern California standing in for the hospital.

The hospital name is often shortened by characters and fans to Princeton-Plainsboro or PPTH. It should not be confused with Princeton University, which is nearby in the show's fictional setting but is not the hospital itself.