What fictional medical specialty does House lead in House M.D.?

Dr. Gregory House leads the fictional Department of Diagnostic Medicine in House M.D.

The department investigates patients whose symptoms do not fit an obvious diagnosis or whose previous treatments have failed. House and his team gather evidence, generate possible explanations, and revise their conclusions as new symptoms or test results appear.

Diagnostic medicine is a real area of clinical practice, but the show presents it in a highly dramatized form. In actual hospitals, diagnosis is generally shared across specialties, and difficult patients may involve infectious disease, neurology, radiology, pathology, surgery, and many other departments.

The show often uses the phrase “the differential diagnosis” for the team’s list of possible diseases. That phrase is real medical terminology. The fictional department’s unusual structure lets the series place House at the center of every case while still bringing in specialists when a diagnosis requires them.