What fictional hospital is the main setting of House M.D.?

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The main fictional hospital in House M.D. is Princeton-Plainsboro Teaching Hospital.

The hospital is the workplace for Gregory House, James Wilson, Lisa Cuddy, and the rotating teams of doctors who investigate rare or unexplained illnesses. Its teaching-hospital structure allows the series to combine patient care, medical training, research, and institutional conflict.

Princeton-Plainsboro is presented as being in New Jersey, near Princeton. The show’s exterior hospital shots were filmed at Princeton University’s Frist Campus Center, while many interior scenes were produced on sound stages in California.

The name is fictional, so it should not be confused with Princeton University or a real hospital with a similar title. The setting also helps distinguish House M.D. from other hospital dramas whose fictional institutions use real city names.

Source: Wikipedia · fact-checked Sept. 2026

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