What fictional address does House, M.D. give for Dr. Gregory House’s apartment?

Dr. Gregory House’s fictional apartment address in House, M.D. is 221B Baker Street.

The address directly echoes 221B Baker Street, the famous London home of Sherlock Holmes. House is deliberately modeled in part on Holmes: both characters are brilliant investigators, rely on deduction, use unconventional methods, and have a close friend who helps connect them to ordinary social life.

The reference is one of several Holmes-inspired details in the series. House’s surname resembles “Holmes,” Wilson parallels Dr. Watson in broad structural terms, and many episodes follow a puzzle-solving pattern in which hidden clues eventually explain an apparently impossible case.

The address is fictional within the show and should not be treated as proof that House lives in London. The series places House in New Jersey, and the Baker Street reference functions as an intentional literary homage rather than a change of setting.