What are Gregory House’s two medical specialties in House M.D.?

Gregory House’s two medical specialties in House M.D. are infectious disease and nephrology.

House is presented as a board-certified diagnostician with expertise in infectious disease and nephrology. Infectious disease concerns illnesses caused by pathogens and other complex infections, while nephrology focuses on the kidneys and related disorders. His unusual combination helps explain why he is particularly comfortable with systemic illnesses that affect multiple organs.

The series usually emphasizes House’s position as head of Diagnostic Medicine rather than depicting him practicing only within either specialty. That distinction is important: diagnostic medicine is his hospital department, while infectious disease and nephrology describe his specialist training.

Viewers may also associate House with neurology because many cases involve the brain or nervous system, but neurologist Eric Foreman is the team’s specialist in that field. House’s cane and leg condition are central character details, yet they do not change the official specialties given to him in the series.