What address is associated with Gregory House’s home in House, M.D.?

Gregory House’s home address in House, M.D. is 221B Baker Street.

The address is a direct reference to Sherlock Holmes, whose fictional London residence is 221B Baker Street. House is modeled in part on Holmes: both are exceptionally observant problem-solvers, both can be abrasive and socially unconventional, and both rely on a trusted friend who challenges their judgments.

House’s address appears as part of the show’s deliberate literary pattern. Other Holmes parallels include the names House and Wilson, the use of deductive reasoning, and the focus on solving cases that initially resist ordinary explanations.

The reference does not mean House lives in London. The series places him in New Jersey, and the address functions as an allusion rather than a realistic geographic detail. It is also distinct from the Sherlock Holmes Museum’s modern visitor-address conventions and from the fictional address 221A Baker Street.