What address does Dr. House give for his home in House M.D.?

Dr. House gives his home address as 221B Baker Street in House M.D.

The address is a direct reference to 221B Baker Street, the famous London home of Sherlock Holmes. House is modeled in part on Holmes, so the repeated address functions as one of the show's clearest literary clues. Both characters are brilliant investigators who rely on deduction and maintain complicated relationships with their more conventional friends.

In the series, House's home is in Princeton, New Jersey, making the London street address deliberately incongruous. The reference is not meant to suggest that House literally lives in London. It is an Easter egg linking the medical detective to his fictional predecessor.

The number is often confused with 221A Baker Street, but Holmes's canonical address is 221B. The reference also differs from real-world questions about the historical location of Holmes-related exhibits and businesses on Baker Street.