House M.D. premiered on the Fox network in 2004.
The series first aired on November 16, 2004, after its original planned premiere date was moved. Fox commissioned the medical drama as a distinctive procedural centered on diagnosis rather than conventional emergency-room action.
Its central format followed House and his diagnostic team as they investigated puzzling illnesses at the fictional Princeton-Plainsboro Teaching Hospital. Episodes typically presented a difficult case, competing hypotheses, tests, complications, and a final diagnosis.
House became one of Fox’s most successful scripted series. It was broadcast in the United States from 2004 until 2012 and developed a large international audience. The network setting is sometimes confused with the fictional hospital, but Fox was the broadcaster; Princeton-Plainsboro is part of the show’s story world.