On what date did the medical drama House M.D. first premiere on television?

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House M.D. premiered on November 16, 2004.

The series debuted on Fox in the United States as a medical drama centered on the unconventional diagnostician Gregory House. Its first episode, “Pilot,” introduced House and his diagnostic team at the fictional Princeton-Plainsboro Teaching Hospital in New Jersey.

The premiere date is sometimes confused with the date of the show’s first international broadcasts or with the date of its series finale. The American series finale aired much later, on May 21, 2012. House M.D. ultimately ran for eight seasons.

The program quickly became one of Fox’s signature scripted dramas. Its distinctive formula combined difficult medical cases, hospital politics, House’s abrasive personality, and recurring mysteries about unexplained symptoms. Although episodes often used rare diseases as plot devices, the show also explored addiction, disability, friendship, professional ethics, and the emotional cost of medical decision-making.

Source: Wikipedia · fact-checked Oct. 2026

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