On what date did House M.D. first premiere on the Fox network?

House M.D. first premiered on the Fox network on November 16, 2004.

The premiere introduced viewers to Gregory House, a diagnostician whose unconventional methods and difficult personality drive the medical drama. The pilot establishes his team, his chronic leg pain, his dependence on a cane, and the hospital environment in which he investigates a rapidly worsening illness.

The series was created by David Shore and developed with executive producer Bryan Singer. Its launch followed Fox’s earlier success with medical programming while giving the genre a different structure: instead of focusing mainly on routine hospital care, House M.D. built episodes around diagnostic puzzles.

The program eventually ran for eight seasons. Its United States broadcast finale aired in 2012, but the November 2004 premiere remains the starting point for the show’s original network run. International release dates varied, so a country’s local premiere date may differ from the Fox debut.