House M.D. never won the Primetime Emmy Award for Outstanding Drama Series. Although the show received multiple Emmy nominations, it did not win the top drama-series prize.
The series was widely recognized during its run, especially for Hugh Laurie’s performance, writing, directing, and technical work. Its lack of a drama-series victory is therefore easy to overlook when recalling its awards history. The show competed during an era that included several acclaimed television dramas.
This answer concerns the Outstanding Drama Series category, not all Emmy categories. House M.D. did receive Primetime Emmy recognition in other areas, and individual performers and contributors earned nominations. It is also separate from the Golden Globe Awards, where Hugh Laurie won for acting. These distinctions explain why award summaries can make the series seem like an Emmy winner even though it did not take the main drama prize.