House M.D. first premiered in 2004.
The medical drama debuted on Fox on November 16, 2004, with “Pilot,” the episode that introduced Gregory House and his diagnostic team. The series was created by David Shore and developed with executive producer Katie Jacobs and director Bryan Singer.
Its premise centered on a specialist who leads a team investigating unusual medical cases, often after ordinary treatments fail. Although the show used fictional cases, its structure drew heavily on diagnostic reasoning. Some viewers remember the show as beginning in 2003 because its development and promotion preceded the broadcast, but the television premiere year was 2004.