In what U.S. state is Grey's Anatomy's main city setting, Seattle?

In what U.S. state is Grey's Anatomy's main city setting, Seattle? The answer is Washington.

Grey's Anatomy is set primarily in Seattle, Washington, where the fictional Seattle Grace Hospital becomes Seattle Grace Mercy West and later Grey Sloan Memorial Hospital. The Pacific Northwest setting gives the series its recognizable rainy atmosphere and connects the hospital to landmarks such as the Space Needle and Seattle waterfront.

The show's creators chose Seattle partly to distinguish the drama from ER, which was set in Chicago. However, the setting and filming location are easy to confuse: much of the series is filmed in Los Angeles, California, with additional work in Vancouver and occasional Seattle locations. California is therefore associated with production, not the story's main city.

The hospital's changing names reflect major story events, including the merger with Mercy West and the deaths of Lexie Grey and Mark Sloan. Seattle remains the fictional hospital's geographic home throughout those changes.