In the TV series House M.D., on what date did the series premiere on Fox?

House M.D. premiered on Fox on November 16, 2004.

The medical drama was created by David Shore and developed with executive producer Katie Jacobs and director Bryan Singer. Its central character, Dr. Gregory House, leads a diagnostic team at the fictional Princeton-Plainsboro Teaching Hospital in New Jersey. The premiere introduced the show's distinctive formula: a puzzling case, competing diagnoses, medical tests, and House's unconventional reasoning.

The series began during Fox's 2004–05 television season. Its first episode was titled “Pilot,” although it is also commonly identified simply as “Everybody Lies,” a phrase closely associated with House's worldview. The program quickly became one of Fox's most recognizable dramas.

The premiere date is sometimes confused with the date of the pilot's production or with the start of a later season. House M.D. ultimately ran for eight seasons, making its November 2004 broadcast debut the beginning of a long-running network series.