Dr. Gregory House’s medical specialties in House M.D. are nephrology and infectious disease. Nephrology is the medical specialty concerned with the kidneys, kidney function, fluid balance, and related disorders.
House’s expertise helps explain why the series frequently focuses on unusual systemic illnesses. Kidney problems can affect many parts of the body, while infectious diseases can produce symptoms that mimic autoimmune, neurological, or psychiatric conditions. The combination gives House a broad diagnostic range.
A common mix-up is identifying House only as an infectious-disease specialist. The show repeatedly presents both fields as central to his professional identity. His specialty is distinct from urology, which is a surgical and medical field dealing with the urinary tract and male reproductive system.
The character’s diagnostic work is fictionalized for drama, but the specialties themselves are real branches of medicine. House’s diagnostic department is portrayed as applying knowledge from these fields to difficult cases that other physicians have not solved.