In House M.D., Dr. Lisa Cuddy was played by Lisa Edelstein.
Edelstein portrayed Cuddy from the series premiere in 2004 through the end of season 7. Cuddy is the dean of medicine and administrator of Princeton-Plainsboro Teaching Hospital, placing her in the difficult position of managing House while also valuing his extraordinary diagnostic ability.
Cuddy and House have a long professional history and a complicated personal relationship. She frequently disciplines him for breaking rules, invading privacy, or endangering hospital operations, yet she protects his department because his team solves cases other doctors cannot.
Lisa Edelstein left House after season 7, so Cuddy does not appear as a regular character in season 8. The role is sometimes mixed up with other major female doctors in the show, especially Allison Cameron, played by Jennifer Morrison, and Remy “Thirteen” Hadley, played by Olivia Wilde.