David Shore created House M.D., the medical drama starring Hugh Laurie as Gregory House. Shore also served as a writer and executive producer during the series’ run.
The show’s central idea was a brilliant but difficult physician who solves unusual cases through diagnostic reasoning. House’s character was strongly shaped by Sherlock Holmes, including his observational skills, abrasive personality, drug dependence, and a surname echoing Holmes’s residence. The medical cases supplied the procedural structure, while House’s relationships provided the continuing drama.
Shore had previously worked in television writing and production before developing the series for Fox. Bryan Singer directed the pilot and became an executive producer, but he was not the show’s creator. That distinction is a common source of confusion because Singer’s involvement was prominent in the early production and publicity.