In House M.D., which medical specialty does Gregory House lead as department head?

In House M.D., Gregory House leads the Department of Diagnostic Medicine.

House’s department specializes in solving complex cases that have resisted ordinary diagnosis. Rather than treating one organ system exclusively, the team combines internal medicine with knowledge from infectious disease, neurology, immunology, genetics, toxicology, and other fields.

The department is fictionalized for dramatic storytelling, but its central idea reflects real diagnostic practice: physicians gather a history, examine the patient, form competing hypotheses, and test them against evidence. House’s teams frequently use differential diagnosis, a structured process for comparing possible causes of illness.

A common mix-up is calling House a neurologist or an infectious-disease specialist. The series establishes that he is board-certified in both nephrology and infectious disease, but his hospital job is running diagnostics. The distinction matters because his unusual cases often require consultations with several clinical specialties before the team reaches a conclusion.