In House M.D., which medical condition does Dr. Remy Hadley inherit from her mother?

In House M.D., Dr. Remy Hadley inherits Huntington’s disease from her mother.

Huntington’s disease is an inherited neurodegenerative disorder caused by a pathogenic expansion in the HTT gene. It is typically autosomal dominant, meaning a child of an affected parent has a 50 percent chance of inheriting the altered gene. Hadley’s family history and her decision about genetic testing are important parts of her character arc.

The series uses her diagnosis to explore uncertainty, privacy, relationships, and the difference between carrying a genetic mutation and already having severe symptoms. This is why the condition is sometimes confused with another neurological illness shown in a medical drama, but Huntington’s disease is the specific diagnosis connected to Thirteen. The condition can cause involuntary movements, changes in cognition, and psychiatric symptoms, with onset and progression varying among individuals.