In House, M.D., which leg was injured by House's muscle infarction?

In House, M.D., House's muscle infarction injured his right leg.

Before the series begins, Gregory House suffers an infarction in the quadriceps muscle of his right leg. The injury leaves him with chronic pain and a limp, and he commonly walks with a cane. His dependence on the painkiller Vicodin becomes one of the show's major personal and professional storylines.

House's leg injury is not simply a background detail. It helps explain his guarded personality, physical limitations, and antagonistic relationship with colleagues who worry about his drug use. Several episodes revisit the medical and emotional consequences of the infarction, including questions about treatment and pain management.

The specific side is easy to reverse because House's cane, posture, and movement are often presented quickly on screen. The canonical detail is the right leg. The muscle infarction affects the quadriceps, a group of muscles at the front of the thigh, rather than being described as a conventional broken bone.