In House M.D., which leg was injured before Gregory House began using a cane?

Gregory House injured his right leg before he began using a cane in House M.D. The injury resulted in muscle death and left him with chronic pain and a permanent limp.

House’s leg condition is central to his character. He relies on Vicodin to manage pain, and the injury affects his posture, walking style, mood, and relationships. The show gradually reveals more about the medical crisis and the treatment decisions that shaped his life.

The injured side can be confused because the cane is often shown on the opposite side of the body for support. House commonly carries the cane in his left hand, which helps support the right leg. That visual detail does not change the canonical fact: the damaged leg is his right leg.