In House, M.D., which character is portrayed by Robert Sean Leonard?

Robert Sean Leonard portrays Dr. James Wilson in House, M.D.

Wilson is the head of the Department of Oncology at Princeton-Plainsboro Teaching Hospital. He is House’s closest friend and often acts as a moral, emotional, and practical counterweight to House’s antisocial behavior.

Their friendship is one of the series’ central relationships. Wilson usually understands House better than other colleagues do, but he also challenges House when House’s actions harm patients, coworkers, or friends.

Wilson’s medical specialty is oncology, the field concerned with cancer. The show uses his work and personal life to explore difficult decisions involving diagnosis, treatment, relationships, and end-of-life care. Robert Sean Leonard, an American actor, remained a major cast member across the series, although his character’s storyline changes substantially in the final season.