In House M.D., which actress portrays hospital dean Dr. Lisa Cuddy?

Lisa Edelstein portrays Dr. Lisa Cuddy, the hospital dean, in House M.D. Cuddy is both House's supervisor and one of the few administrators willing to defend his diagnostic value.

Edelstein joined the main cast as Cuddy, whose responsibilities include budgets, staffing, discipline, and institutional policy. Her scenes with House often turn medical disagreements into conflicts about authority, risk, and professional responsibility.

Cuddy also has a complicated personal relationship with House, and the series develops that relationship over several seasons. Edelstein left the regular cast after the seventh season, so Cuddy is absent from the show's final season. Jennifer Morrison played Allison Cameron, while Olivia Wilde played Remy “Thirteen” Hadley.