In House M.D., which actor plays Dr. Lisa Cuddy?

Lisa Edelstein plays Dr. Lisa Cuddy in House M.D.

Cuddy is the dean of medicine and hospital administrator at Princeton-Plainsboro Teaching Hospital. Her position places her in regular conflict with Gregory House, whose unconventional investigations and disregard for hospital rules repeatedly challenge administrative authority. Their professional relationship also develops into a romantic storyline during the series.

Edelstein joined the principal cast as Cuddy and remained a major character through the show’s seventh season. She left the series before season eight, so Cuddy does not appear as a regular character in the final season. The actor’s first name and the character’s first name are both Lisa, a detail that can cause confusion when credits or cast lists are read quickly. Edelstein is also known for work outside House M.D., including film, television, and voice acting.