In House M.D., which actor played Dr. Gregory House throughout the series?

Hugh Laurie played Dr. Gregory House throughout the television series House M.D.

Laurie, an English actor, portrayed the brilliant but abrasive diagnostician from the show's premiere in 2004 through its finale in 2012. His performance combined dry humor, physical comedy, emotional restraint, and a deliberately American accent. The role made Laurie internationally famous as a dramatic television lead, despite his earlier reputation for British comedy.

House is a doctor whose expertise is balanced by severe personal flaws, including dependence on Vicodin and difficulty maintaining relationships. Laurie’s performance helped make those contradictions central to the series rather than treating House as a conventional heroic physician.

A common mix-up is confusing Laurie with Robert Sean Leonard, who played House’s best friend, Dr. James Wilson. Laurie also received multiple major acting nominations for House, including Emmy nominations, and won two Golden Globe Awards for the role.