In House M.D., what neurological disease does Remy “Thirteen” Hadley inherit?

In House M.D., Remy “Thirteen” Hadley inherits Huntington's disease.

Huntington's disease is a hereditary neurodegenerative disorder caused by a mutation in the HTT gene. It is usually inherited in an autosomal dominant pattern, meaning a person who carries the altered gene has a substantial chance of passing it to each child. Symptoms can include involuntary movements, cognitive changes, and psychiatric difficulties.

The diagnosis becomes a major personal storyline for Thirteen because her mother also had the disease and Thirteen eventually learns that she carries the mutation. The show uses her medical knowledge to explore genetic testing, uncertainty, and decisions about relationships and future care. Huntington's disease is not the same as Parkinson's or Alzheimer's disease, although all can involve neurological symptoms.