In House, M.D., what is the title of the two-part season-four finale involving House's memory loss?

The two-part season-four finale of House, M.D. is titled “House's Head” and “Wilson's Heart.”

“House's Head” follows Gregory House after he suffers a head injury and cannot remember a crucial event involving a patient. He tries to reconstruct the missing hours while experiencing disturbing symptoms and fragmented memories. The story continues in “Wilson's Heart,” which reveals the medical and emotional consequences of the mystery.

The paired titles deliberately shift attention between the two central friends. The first episode focuses on House's damaged memory and investigative effort; the second emphasizes James Wilson and the personal stakes of the case. Together, they form one continuous finale rather than two unrelated stories.

A common mix-up is identifying “Euphoria” or “No Reason” as the season-four conclusion. Those are earlier season-four episodes. “House's Head” is episode 15 of the season, followed by “Wilson's Heart,” episode 16, which closes the season.