In House M.D., Hugh Laurie plays the diagnostician Gregory House.
House is the central character of the medical drama, which follows his work solving unusually difficult diagnostic cases. He leads a team at the fictional Princeton-Plainsboro Teaching Hospital in New Jersey.
The character is known for his exceptional medical reasoning, sarcastic manner, dependence on a cane, and addiction to Vicodin. His methods often create conflict with colleagues, patients, and hospital administrators.
Gregory House was deliberately designed with similarities to Sherlock Holmes. Both characters are brilliant investigators who rely on deduction, live at 221B in their respective stories, and have a close friend named Wilson or Watson. The surname House also echoes Holmes's name through the idea of a “house” and “Holmes” sharing a similar sound in some adaptations, although House is a distinct character.