Gregory House’s closest friend, James Wilson, has the surname Wilson in House M.D.
Dr. James Wilson is an oncologist and the head of the Department of Oncology at Princeton-Plainsboro Teaching Hospital. He and House have a long, complicated friendship that frequently places Wilson between House and the hospital’s rules, patients, or administrators.
Wilson is played by Robert Sean Leonard. Unlike House, Wilson is generally more diplomatic and emotionally open, although the series shows that his personal and professional life can also be complicated. Their friendship is a central relationship throughout the drama and often reveals sides of House that are hidden from colleagues.
The character’s medical specialty is important to the show’s cases because Wilson can provide expert advice about cancer and end-of-life care. His surname is sometimes confused with the names of other major doctors, including Lisa Cuddy, Eric Foreman, and Robert Chase.