In House M.D., what is the name of House's best friend, Dr. Wilson?

In House M.D., Dr. Wilson's full name is James Wilson.

James Evan Wilson is an oncologist at Princeton-Plainsboro and House's closest friend. Robert Sean Leonard played the character throughout the series. Wilson's medical specialty gives him a different perspective from House's diagnostic approach, while his empathy often balances House's blunt and confrontational behavior.

Wilson and House have a famously complicated friendship. They argue, investigate cases together, and repeatedly become involved in each other's personal lives. Wilson also acts as one of the few people willing to challenge House directly, even when House resists advice or behaves irresponsibly.

Viewers may remember the character simply as “Wilson,” and the show uses that surname most of the time. His first name is James, not John. “Dr. Wilson” is also distinct from other doctors in the series, including James Cameron and Robert Chase.