In House M.D., what is the name of House’s best friend and oncologist colleague?

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James Wilson is House’s best friend and oncologist colleague in House M.D.

Dr. Wilson is portrayed as compassionate, socially skilled, and more willing than House to consider the emotional effects of illness. His friendship with House supplies one of the series’ main relationships, balancing House’s skepticism and confrontational behavior.

Robert Sean Leonard played Wilson for the entire television series. The character heads the oncology department at the fictional Princeton-Plainsboro Teaching Hospital and frequently becomes involved in House’s cases, personal problems, and disputes with hospital administrators.

A common mix-up is to identify Wilson as House’s supervisor or diagnostic-team member. He is neither: Lisa Cuddy is the hospital administrator who oversees House, while Wilson works in oncology. Wilson’s surname is also sometimes confused with Cameron, another doctor on House’s original diagnostic team.

Source: Wikipedia · fact-checked Oct. 2026

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