In House M.D., what is the name of House’s best friend and hospital oncologist?

In House M.D., James Wilson is Gregory House’s best friend and the hospital’s head of oncology.

Wilson provides a moral and emotional counterweight to House. He is generally more empathetic and socially conventional, yet he repeatedly remains loyal to House despite House’s impulsive decisions and damaging behavior. Their friendship is one of the show’s longest-running relationships.

The character is played by Robert Sean Leonard. Wilson’s oncology work also gives the series a recurring connection to cancer diagnosis and end-of-life decisions, while his personal story develops through several marriages and complicated relationships. His first name is James, although characters often address him by his surname, which can cause confusion with other physicians in the hospital.