In House M.D., what is the name of Dr. House’s limp-causing leg condition?

Dr. House’s limp-causing leg condition is a quadriceps infarction in House M.D.

House suffers an infarction, meaning loss of blood supply and tissue death, in the quadriceps muscle of his thigh. The injury causes permanent muscle damage, chronic pain, and the limp for which he uses a cane. It is one of the most important facts in the character’s medical history.

The series reveals that the infarction was initially misdiagnosed. House eventually undergoes a risky procedure that removes damaged muscle, but the treatment leaves him with lasting disability rather than restoring normal function. His later reliance on Vicodin is closely connected to this pain.

The condition is sometimes loosely described by viewers as a blood clot or a leg injury. Those descriptions do not give the specific diagnosis. House’s medical condition is a quadriceps infarction, and the affected muscle is in his right thigh.