In House M.D., oncologist Dr. Wilson’s first name is James.
James Wilson is Gregory House’s closest friend and a major supporting character throughout the series. He works in oncology at Princeton-Plainsboro Teaching Hospital, treating patients with cancer while also advising House during medical and personal crises. Their friendship is central to the show because Wilson often provides empathy and social judgment that House lacks.
The character is played by Robert Sean Leonard. The show usually calls him “Wilson,” so viewers can easily overlook his first name. His full name appears in character information and story details rather than in the everyday dialogue used by colleagues.
Wilson’s role also creates a contrast with House’s specialty. Oncology focuses on cancers and their treatment, while House’s diagnostic team investigates unexplained medical problems across many specialties. Wilson’s eventual diagnosis with thymoma in the final season becomes a major storyline, giving the friendship an especially important place in the series finale.