In House M.D., what is House’s apartment address?

In House M.D., House’s apartment address is 221B Baker Street.

The address is a direct reference to Sherlock Holmes, whose famous London residence is 221B Baker Street. House is deliberately modeled in several ways on Holmes: both are exceptionally observant investigators, both rely on deduction, and both have a close companion who offers a moral and emotional counterbalance. James Wilson fills that role in the medical drama, much as Dr. Watson does in the detective stories.

House’s fictional address is in Princeton, New Jersey, rather than London. The reference is therefore an allusion rather than a claim that the character lives in the original Sherlock Holmes setting. The apartment detail is one of several clues connecting the series to Holmes, including the names House and Holmes and the show’s emphasis on solving apparently impossible cases.