In House M.D., what is Dr. House’s second medical specialty alongside nephrology?

Dr. House’s second medical specialty alongside nephrology is infectious disease.

House is described as a double board-certified physician in nephrology and infectious disease. These specialties help explain his ability to evaluate kidney disorders, systemic illnesses, unexplained fevers, and infections that affect multiple organs. The show’s cases often move across specialties, but House’s stated formal expertise is especially associated with these two fields.

Nephrology focuses on the kidneys and related disorders, while infectious disease concerns illnesses caused by bacteria, viruses, fungi, parasites, and other pathogens. In the series, House’s diagnostic role allows him to apply knowledge from both areas while also drawing on other medical disciplines.

The fact is easy to misremember because House routinely diagnoses neurological, autoimmune, cardiac, and toxicological conditions. Those cases do not change his listed specialties. The question asks for the specialty paired with nephrology in House’s professional background, and that specialty is infectious disease.