In House M.D., what is Dr. House’s medical specialty pairing?

Dr. Gregory House specializes in infectious disease and nephrology in House M.D.

Those specialties help explain why House is unusually suited to difficult diagnostic cases. Infectious disease concerns illnesses caused by pathogens, while nephrology focuses on the kidneys and related disorders. The combination gives House expertise across systemic illness, organ failure, and puzzling symptoms.

House is introduced as the head of diagnostic medicine at Princeton-Plainsboro, rather than as a conventional ward physician. His team brings in specialists when cases involve areas outside his expertise, but House leads the process of generating and testing possible diagnoses.

The character’s leg injury is also medically important to his story. A vascular infarction damaged muscle in his thigh, leaving him with chronic pain and a limp. He uses a cane and relies on Vicodin, creating a continuing conflict between pain control, addiction, and his professional work.