In House M.D., what is Dr. Gregory House’s medical specialty?

In House M.D., Dr. Gregory House specializes in diagnostic medicine, leading a team that investigates difficult and unusual cases.

Diagnostic medicine in the series functions as a multidisciplinary field. House’s team draws on specialties such as neurology, immunology, oncology, and infectious disease to identify illnesses that other doctors have not explained. The department is fictionalized for dramatic storytelling, but its cases often combine real symptoms and medical concepts.

House is also described as board-certified in infectious disease and nephrology. Those specialties help explain his particular expertise, but diagnostic medicine is the department and professional role most closely associated with him in the show.

His approach emphasizes differential diagnosis: doctors list possible causes, test them, and eliminate options as new evidence appears. This recurring structure gives the series its distinctive medical-mystery format.