Plainsboro is the fictional New Jersey municipality paired with Princeton in the name Princeton-Plainsboro Teaching Hospital. The hospital’s name suggests a regional institution serving both communities.
House M.D. uses Princeton and Plainsboro as a combined fictional setting rather than depicting a real hospital called Princeton-Plainsboro. Real exterior footage was filmed at the Sepulveda Ambulatory Care Center in Los Angeles, while interiors and other locations were produced for the series.
Plainsboro is also the name of a real township in Mercer County, New Jersey, near Princeton. The show’s invented hospital therefore sounds geographically plausible, which can lead viewers to mistake the fictional institution for an actual medical center.