In House M.D., what fictional address is associated with Gregory House's apartment?

Gregory House's apartment in House M.D. is associated with the fictional address 221B Baker Street.

The address is a direct reference to 221B Baker Street, the London home of Sherlock Holmes in Arthur Conan Doyle's detective stories. House is modeled partly on Holmes, so the address reinforces the show's detective-story influences.

House's diagnostic method also parallels Holmes's approach: he observes unusual details, tests competing explanations, and often reaches a solution that other people overlook. James Wilson functions as a counterpart to Dr. Watson, while House's surname itself resembles Holmes's.

The reference does not mean that House lives in London. The character works in New Jersey, and the Baker Street address is an allusion rather than a realistic location for the series. It is therefore best understood as a literary clue about House's character and investigative style.