House, M.D. ran for eight seasons before ending in 2012.
The medical drama premiered on Fox on November 16, 2004, and concluded on May 21, 2012. Across its run, the show followed Gregory House and changing teams of physicians who investigated unusual medical cases. Its format combined a weekly diagnostic mystery with continuing stories about relationships, addiction, professional ethics, and hospital politics.
The eight seasons contained 177 episodes. The cast and structure changed over time: House’s original diagnostic fellows were eventually replaced or supplemented by later doctors, while recurring characters such as Wilson and Cuddy remained important. The final season continued after major cast changes and ended with House and Wilson’s friendship at the center of the story.
The episode count is sometimes confused with the number of seasons because the show had a long run and many international broadcast schedules. Eight is the season total, not the number of regular doctors on House’s original team or the number of years between the premiere and finale.